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Watch out these symptoms and factors leading to this deficiency. Usually deficiency of this enzyme doesn’t harm unless there is metabolic stress in body which can be either to oral medicines or food items like beans, tonic water etc. G6PD is defined as Glucose 6 Phosphate Dehydrogenase enzyme Deficiency which is important in red blood cell metabolism and helps to protect red blood cells from reactive oxygen species. It is a haemolytic anaemia (red blood cell enzymopathy) which has X-linked recessive genetic basis. It was discovered in 1950 accidently.